Which of the following conditions is conclusively presumed to be a Permanent Total Disability (PTD)?

Loss of both hands or use of them is a condition that is conclusively presumed to result in Permanent Total Disability (PTD) under West Virginia's Workers' Compensation laws. This presumption exists because the complete loss or use of both hands significantly impacts an individual's ability to perform daily living activities and gainful employment, essentially rendering them incapable of returning to the labor market in any capacity.

Other conditions, while serious and potentially disabling, do not have the same level of immediate and conclusive presumption of being permanently totally disabled. For instance, the loss of one foot, one hand, or partial vision may still allow an individual to engage in some form of work or manage daily tasks, thus not automatically qualifying them for a PTD status. Therefore, the specific severity of losing both hands is recognized legally as a definitive case for PTD, reflecting the understanding of the profound impairment it causes.